Keythe is a graduate of UCLA and is an active member of the Actors' Gang and Evidence Room theatre companies. Keythe has written for, produced and/or voice-directed episodes of Rugrats, As Told by Ginger and The Wild Thornberries for Klasky/Csupo Inc. Keythe is also the co-author of Bat Boy: The Musical (with Brian Flemming and Laurence O'Keefe) which is the recipient of the 2001 Outer Critics Circle and Lucille Lortel Awards for Best Off-Broadway Musical.